Where Does Optimal Well-Being Start?

Which aspects play the biggest part? Many assume germs cause disease, and that avoiding them is the key to staying healthy. But a different theory suggests these pathogens seize the opportunity to settle in an already ailing microbiome. This is the theory of “biological terrain,” championed by Antoine Béchamp, a pioneer of microbiology who never gained much notoriety. He declared that “the primary cause of disease is in us, always in us.”1 This “primary cause” is the place where bad bacteria pitch camp: unhealthy biological terrain. So, how do we cultivate top-notch terrain? Perhaps a probiotic would introduce a host of helpful organisms? That may be, but if they are to thrive, the stage must be set before they arrive. 

READ MORE: The Terrain of Health and 3 Easy Ways to Reduce Inflammation

Gatekeepers of Your Biological Terrain

Our terrain exists along the gut membrane, the bedrock of which is composed of epithelial cells joined by tight junctions. These tight junctions act as “selective gatekeepers that regulate the absorption of macronutrients and compose a frontline of defense.”2 The structure is that of tiles laid together with grout, but the function is not strictly to keep anything in or out. This terrain drives the expression of its own microbial activity, determining what type of tiny beings populate it. Like one of Earth’s greater ecosystems, the gut’s environmental foundation heavily influences which flora and fauna flourish. Across the epithelial wall a mucous layer is spread, and this is where those microbes roam. The cells active in the mucosa alter the thickness of this layer as needed, and they sample it while searching for pathogenic bacteria. If a threat is found, they will secrete antimicrobials to secure it. This intelligent, multi-layered membrane is the most active line of communication between our human cells and the microbiome, and the information that’s traded back and forth is vital in maintaining our vitals. 

RESTORE Offers Support

The inter-cellular signals being transmitted drive functions of the greater systems throughout the body, such as peristalsis, circadian rhythm, and hormone production. Even one’s mental state is affected by the condition of the microbiome, as there is a strong correlation between dysbiosis and mood disorders like anxiety and depression.3 The integrity of the gut’s terrain is clearly critical if one is to be wholly healthy. This is where RESTORE offers support by maintaining healthy tight junctions. These cell-to-cell connections, the mortar in the gut wall, form a stable structure resilient to assault from environmental toxins, food additives, and other threats such as gluten and glyphosate.2,4 By supporting this cellular scaffolding, RESTORE facilitates the proper functioning of the body’s maintenance systems, which regulate our terrain’s pH level, population, mucosa, and more. When these various elements of equilibrium are in tune, good microbial guests may proliferate. Communication can then commence between them and the human body. 

READ THE SCIENCE: How RESTORE Supports Communication in the Gut

With the terrain well-tended, and the body’s systems balanced, the bacterial buddies coming in a probiotic dose have a much better chance for success. Just think, a seed won’t germinate in any old dirt; it needs rich, healthy soil. Preparing a proper garden bed and growing plants in it are separate efforts, and the situation within us is similar. Use RESTORE to prepare a fit foundation in the gut before introducing new members to the microbiome, and they will be far more likely to call it home. Then, when billions of those happy campers are communicating with each other and beyond, the body will benefit from a self-regulated balance, allowing it to be its own source of all-around well-being. 


  1. Mister Seun Ayoade. The Differences Between the Germ Theory, the Terrain Theory and the Germ Terrrain Duality Theory; JOJ Nurse Health Care. 2017; 4(2): 555631. 
  2. Gildea JJ, Roberts DA, Bush Z (2016) Protection against Gluten-mediated Tight Junction Injury with a Novel Lignite Extract Supplement. J Nutr Food Sci 6: 547. 
  3. Evrensel A, Ceylan ME. The Gut-Brain Axis: The Missing Link in Depression. Clin Psychopharmacol Neurosci. 2015;13(3):239–244.
  4. Gildea JJ, Roberts DA, Bush Z. Protective Effects of Lignite Extract Supplement on Intestinal Barrier Function in Glyphosate-Mediated Tight Junction Injury. J Clin Nutr Diet. 2017, 3:1.